well, with my magelo, 3 monks for dps, plus a sham, 1 cleric with about... ( magelo inc )
http://eq.magelo.com/profile/1382414 -a slightly outdated magelo of one of the clerics
i've tried using that cleric single, and problem is, cheals are too long to cast still, with sham slow / shield out, etc, shyra still hits too hard, so i keep a second cleric there for the backup, but i think with a slightly stronger tank, i think shyra could definately be one cleric - chealed. now the stamina has alot more to do with the dps you're sporting,
can you estimate how much dps you'll be having there?
we have probably about... 2,000 + 1,000 + 500 + 500 + whatever panther does so... at least 4,000, and more for pather procs on ... four people. so,
4,000+dps, and the tank i have above, with the cleric listed, the cleric barely makes it, and more likely ooms if he chain cheals alone.
so bit more mana, bit more ac hp, and my listed cleric, my listed paladin, plus teh mentioned setup, *could handle a 1 cleric shyra and kill before oom.